Cathepsin K 抗体 (AA 163-274) (CF®740)
Quick Overview for Cathepsin K 抗体 (AA 163-274) (CF®740) (ABIN7650709)
抗原
See all Cathepsin K (CTSK) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 163-274
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原理
- Cathepsin K (Marker of Tumor Invasiveness)(CTSK/2793), CF740 conjugate
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产品特性
- Cathepsin K is a lysosomal and secreted cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human Cathepsin K protein (around aa 163-274)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Human liver or breast tissue (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Cathepsin K (CTSK)
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别名
- Cathepsin K
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背景
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Synonyms: Cathepsin K, Cathepsin O, Cathepsin O1, Cathepsin O2, Cathepsin X, CTSK
Gene Symbol: CTSK
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分子量
- 39 kDa
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基因ID
- 1513
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UniProt
- P43235
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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