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Cathepsin K 抗体 (AA 163-274) (CF®640R)

This anti-Cathepsin K antibody is a 小鼠 单克隆 antibody detecting Cathepsin K in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7650700
发货至: 中国

Quick Overview for Cathepsin K 抗体 (AA 163-274) (CF®640R) (ABIN7650700)

抗原

See all Cathepsin K (CTSK) 抗体
Cathepsin K (CTSK)

适用

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宿主

  • 84
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小鼠

克隆类型

  • 87
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单克隆

标记

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This Cathepsin K antibody is conjugated to CF®640R

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

CTSK-2793
  • 抗原表位

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    AA 163-274

    原理

    Cathepsin K (Marker of Tumor Invasiveness)(CTSK/2793), CF640R conjugate

    产品特性

    Cathepsin K is a lysosomal and secreted cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment of human Cathepsin K protein (around aa 163-274)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Human liver or breast tissue (IHC).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Cathepsin K (CTSK)

    别名

    Cathepsin K

    背景

    Synonyms: Cathepsin K, Cathepsin O, Cathepsin O1, Cathepsin O2, Cathepsin X, CTSK

    Gene Symbol: CTSK

    分子量

    39 kDa

    基因ID

    1513

    UniProt

    P43235

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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