Cathepsin D 抗体 (AA 104-250) (CF®647)
Quick Overview for Cathepsin D 抗体 (AA 104-250) (CF®647) (ABIN7650655)
抗原
See all Cathepsin D (CTSD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 104-250
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原理
- Cathepsin D (Tumor Marker)(CTSD/2781), CF647 conjugate
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产品特性
- Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human Cathepsin D protein (around aa 104-250)
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亚型
- IgG1, kappa
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anti-Cathepsin D (CTSD) (C-Term) antibody
CTSD 适用: 人, 小鼠, 大鼠, Hamster, 猴, Cow, 兔, Pig, 犬, 豚鼠, 马, Avian, Cat, 小鸡, 驴, 山羊, 绵羊 WB, IHC (p), IF, IHC (fro), IEM 宿主: 山羊 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 66-410) antibodyCTSD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 1-412) antibodyCTSD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 26-412) antibodyCTSD 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 3F12-1B9 unconjugated
anti-Cathepsin D (CTSD) (AA 104-250) antibodyCTSD 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CTSD-3082 unconjugated
anti-Cathepsin D (CTSD) (AA 21-412) antibodyCTSD 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-Cathepsin D (CTSD) (AA 120-407) antibodyCTSD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 104-250) antibodyCTSD 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal CTSD-3276 unconjugated
anti-Cathepsin D (CTSD) (C-Term) antibodyCTSD 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 101-200) antibodyCTSD 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: K-562, A431 or SK-BR3 cells. Kidney, Liver, Lung or Breast.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Cathepsin D (CTSD)
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别名
- Cathepsin D
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背景
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Synonyms: Cathepsin D, CTSD, Lysosomal aspartyl peptidase
Gene Symbol: CTSD
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分子量
- 46 kDa (Procathepsin D), 28 kDa (Cathepsin D)
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基因ID
- 1509
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UniProt
- P07339
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途径
- Peptide Hormone Metabolism
抗原
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