CAPN1 抗体
Quick Overview for CAPN1 抗体 (ABIN7650441)
抗原
See all CAPN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Calpain 1(CAPN1/1530)
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产品特性
- Calpain 1 is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2 - dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpain 1, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain 1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human CAPN1 protein
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亚型
- IgG1, kappa
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anti-Calpain 1 (CAPN1) (AA 625-713) antibody
CAPN1 适用: 人, 小鼠, 大鼠 WB, FACS, IP, IHC (p), IF (cc), IF (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) antibodyCAPN1 适用: 人 WB, ICC, IP, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) antibodyCAPN1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IP, IHC (p), ELISA 宿主: 小鼠 Monoclonal 15C10 unconjugated
anti-Calpain 1 (CAPN1) (AA 515-526) antibodyCAPN1 适用: 人 WB, IHC, IHC (p), ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) (AA 185-234) antibodyCAPN1 适用: 人, Cow, Pig, 山羊, 兔, 绵羊, Bat, 小鸡, 犬, 豚鼠, 马, 猴, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) (AA 300-349) antibodyCAPN1 适用: 人, 小鼠, 大鼠, Cow, Pig, 山羊, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HeLa cells. Skin or Tonsil.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CAPN1 (Calpain 1 (CAPN1))
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别名
- Calpain 1
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背景
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Synonyms: Calpain 1, Calcium dependent protease small subunit 1, Calcium-activated neutral proteinase 1, Calpain 1 large subunit, Calpain mu-type, Calpain-1 catalytic subunit, CANP1, CANPL1, CAPN1
Gene Symbol: CAPN1
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分子量
- ~80 kDa
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基因ID
- 823
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UniProt
- P07384
抗原
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