Recombinant Caldesmon 抗体 (High Molecular Weight)
Quick Overview for Recombinant Caldesmon 抗体 (High Molecular Weight) (ABIN7650418)
抗原
See all Caldesmon (CALD1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- High Molecular Weight
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原理
- Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (rCALD1/820)
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产品特性
- Caldesmon HMW is the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb This antibody recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human CALD1 protein
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亚型
- IgG1, kappa
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anti-Caldesmon 1 (CALD1) (AA 26-207) antibody
CALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6F8D2 unconjugated
anti-Caldesmon 1 (CALD1) (AA 434-531) antibodyCALD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) (pSer789) antibodyCALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人, 大鼠 IHC, StM 宿主: 兔 Monoclonal CALD1-1424R unconjugated Recombinant Antibody
anti-Caldesmon 1 (CALD1) (C-Term) antibodyCALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) (AA 1-240) antibodyCALD1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人, 大鼠 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CALD1-820 unconjugated
anti-Caldesmon 1 (CALD1) (AA 1-538) antibodyCALD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Does not react with rat. Immunohistology (formalin): 0.25-0.5 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA pH 7.5-8.5 for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Uterus, Blood vessels in all tissues, smooth muscle or leiomyosarcoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
- Caldesmon
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背景
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Synonyms: Caldesmon, Caldesmon 1, Caldesmon 1 Isoform 1, CDM, HCAD
Gene Symbol: CALD1
Tissue Expression: Smooth muscle
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分子量
- 150 kDa
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基因ID
- 800
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UniProt
- Q05682
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途径
- Myometrial Relaxation and Contraction
抗原
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