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Caldesmon 抗体 (High Molecular Weight) (Biotin)

This anti-Caldesmon antibody is a 兔 多克隆 antibody detecting Caldesmon in WB, IHC 和 IHC (fp). Suitable for 人 和 大鼠.
产品编号 ABIN7650415
发货至: 中国

Quick Overview for Caldesmon 抗体 (High Molecular Weight) (Biotin) (ABIN7650415)

抗原

See all Caldesmon (CALD1) 抗体
Caldesmon (CALD1) (Caldesmon 1 (CALD1))

适用

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人, 大鼠

宿主

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克隆类型

  • 99
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多克隆

标记

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This Caldesmon antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    High Molecular Weight

    原理

    Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate

    产品特性

    Caldesmon HMW is the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This antibody recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human CALD1 protein fragment

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Uterus, Blood vessels in all tissues, smooth muscle or leiomyosarcoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Caldesmon (CALD1) (Caldesmon 1 (CALD1))

    别名

    Caldesmon

    背景

    Synonyms: Caldesmon, Caldesmon 1, Caldesmon 1 Isoform 1, CDM, HCAD

    Gene Symbol: CALD1

    Tissue Expression: Smooth muscle

    分子量

    150 kDa

    基因ID

    800

    UniProt

    Q05682

    途径

    Myometrial Relaxation and Contraction
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