Recombinant Cadherin-16 抗体 (CF®740)
Quick Overview for Recombinant Cadherin-16 抗体 (CF®740) (ABIN7650257)
抗原
See all Cadherin-16 (CDH16) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 (CDH16/1532R), CF740 conjugate
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产品特性
- This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length CDH16 protein
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亚型
- IgG, kappa
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anti-Cadherin-16 (CDH16) (AA 37-287) antibody
CDH16 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) (AA 353-617) antibodyCDH16 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 WB, FACS, IHC (f) 宿主: 兔 Monoclonal CDH16-1532R unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (AA 19-230) antibodyCDH16 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) (AA 371-507) antibodyCDH16 适用: 人 WB, ELISA, IHC (f), Coat 宿主: 小鼠 Monoclonal CDH16-2125 unconjugated
anti-Cadherin-16 (CDH16) (AA 371-507) antibodyCDH16 适用: 人 ELISA, IHC (f), Coat 宿主: 小鼠 Monoclonal CDH16-2448 unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 WB, FACS, IHC (f) 宿主: 小鼠 Monoclonal rCDH16-1071 unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (AA 1-829) antibodyCDH16 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-516R unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (C-Term) antibodyCDH16 适用: 人 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Immunohistology (formalin): 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA Buffer pH 9.0 for 10-20 min followed by cooling at RT for 20 min. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Normal kidney or renal cell carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Cadherin-16 (CDH16)
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别名
- CDH16
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背景
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Synonyms: Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody
Gene Symbol: CDH16
Tissue Expression: Epithelial cells
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分子量
- 130 kDa
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基因ID
- 1014
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UniProt
- O75309
抗原
-
