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Recombinant beta-2 Microglobulin 抗体

This anti-beta-2 Microglobulin antibody is a 兔 单克隆 antibody detecting beta-2 Microglobulin in WB, FACS, IHC, IF 和 IHC (fp). Suitable for 人 和 Non-Human Primate.
产品编号 ABIN7650059
发货至: 中国

Quick Overview for Recombinant beta-2 Microglobulin 抗体 (ABIN7650059)

抗原

See all beta-2 Microglobulin (B2M) 抗体
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This beta-2 Microglobulin antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

B2M-1857R
  • 原理

    Beta-2 Microglobulin (Renal Failure & Tumor Marker) (B2M/1857R)

    产品特性

    Beta-2 microglobulin is a component of the class I major histocompatibility complex (MHC I) where it functions in antigen processing and presentation. Involved in the presentation of peptide antigens to the immune system. Human Beta-2 microglobulin is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human Beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of Beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human B2M protein

    亚型

    IgG
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.5-1 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    别名

    Beta-2 Microglobulin

    背景

    Synonyms: B2M, Beta 2 microglobulin

    Gene Symbol: B2M

    分子量

    12 kDa

    基因ID

    567

    UniProt

    P61769

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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