BCL10 抗体 (AA 122-168) (Biotin)
Quick Overview for BCL10 抗体 (AA 122-168) (Biotin) (ABIN7649853)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 122-168
-
原理
- BCL10 (MALT-Lymphoma Marker)(151), Biotin conjugate
-
产品特性
- B-cell lymphoma/leukemia 10 (BCL10) is a signaling protein that promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL10 contains an N-terminal caspase recruitment domain (CARD), which is found in a number of apoptotic regulatory molecules. BCL10 is involved in the adaptive immune response, and may be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. A BCL10 translocation is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
免疫原
- Human BCL10 recombinant protein (epitope aa122-168)
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
Positive Control: HepG2 cells. Lymphoma.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
-
Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
有效期
- 24 months
-
-
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
-
别名
- BCL10
-
背景
-
Synonyms: BCL10, BCL-10, B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10
Gene Symbol: BCL10
-
分子量
- 33 kDa
-
基因ID
- 8915
-
UniProt
- O95999
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
-