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Annexin a1 抗体 (CF®488A)

This anti-Annexin a1 antibody is a 小鼠 单克隆 antibody detecting Annexin a1 in IHC, FACS 和 IHC (fp). Suitable for 人.
产品编号 ABIN7649540
发货至: 中国

Quick Overview for Annexin a1 抗体 (CF®488A) (ABIN7649540)

抗原

See all Annexin a1 (ANXA1) 抗体
Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

适用

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小鼠

克隆类型

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单克隆

标记

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This Annexin a1 antibody is conjugated to CF®488A

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

6E4-3
  • 原理

    Annexin A1 / (Hairy Cell Leukemia Marker)(6E4/3), CF488A conjugate

    产品特性

    Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Mixture of native proteins from human bone tissues

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa, A431, K562 cells, human esophagus, placenta and prostate tissues.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

    别名

    Annexin A1

    背景

    Synonyms: Annexin-1, Calpactin-2, Chromobindin-9, Phospholipase A2 inhibitory protein, LPC1, p35

    Gene Symbol: ANXA1

    分子量

    35 kDa

    基因ID

    301

    UniProt

    P04083

    途径

    Hormone Transport
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