Annexin a1 抗体 (CF®640R)
Quick Overview for Annexin a1 抗体 (CF®640R) (ABIN7649514)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Annexin A1 / (Hairy Cell Leukemia Marker)(ANXA1/1671), CF640R conjugate
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产品特性
- Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human Annexin A1 protein
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: A431 and K562 cell lysates. Human esophagus, placenta and prostate tissues.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- Annexin A1
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背景
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Synonyms: Annexin-1, Calpactin-2, Chromobindin-9, Phospholipase A2 inhibitory protein, LPC1, p35
Gene Symbol: ANXA1
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分子量
- 35 kDa
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基因ID
- 301
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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