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APCS 抗体 (AA 143-223) (CF®405S)

This anti-APCS antibody is a 小鼠 单克隆 antibody detecting APCS in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7649434
发货至: 中国

Quick Overview for APCS 抗体 (AA 143-223) (CF®405S) (ABIN7649434)

抗原

See all APCS 抗体
APCS (Amyloid P Component, Serum (APCS))

适用

  • 88
  • 17
  • 13
  • 2
  • 1

宿主

  • 69
  • 35
  • 2
  • 1
小鼠

克隆类型

  • 72
  • 35
单克隆

标记

  • 67
  • 11
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  • 5
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
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This APCS antibody is conjugated to CF®405S

应用范围

  • 72
  • 70
  • 34
  • 29
  • 23
  • 9
  • 9
  • 7
  • 6
  • 5
  • 5
  • 3
  • 1
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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

APCS-3240
  • 抗原表位

    • 14
    • 12
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 143-223

    原理

    Serum Amyloid P / APCS(APCS/3240), CF405S conjugate

    产品特性

    Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer's disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment of human APCS protein (around aa 143-223)

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Human endometrial carcinoma tissue (IHC).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    APCS (Amyloid P Component, Serum (APCS))

    别名

    APCS

    背景

    Synonyms: 9.5S alpha 1 glycoprotein, Amyloid P component serum (APCS), Pentaxin related, Pentraxin 2 (PTX2), Serum Amyloid P (SAP), Serum amyloid P component

    Gene Symbol: APCS

    分子量

    200 kDa (oligomeric), 26 kDa (non-covalently bound subunit), 30 kDa (glycosylated SAP subunit)

    基因ID

    325

    UniProt

    P02743
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