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AMPD3 抗体 (CF®740)

This anti-AMPD3 antibody is a 小鼠 单克隆 antibody detecting AMPD3 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7649180
发货至: 中国

Quick Overview for AMPD3 抗体 (CF®740) (ABIN7649180)

抗原

See all AMPD3 抗体
AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This AMPD3 antibody is conjugated to CF®740

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

AMPD3-901
  • 原理

    Adenosine Monophosphate Deaminase 3 (AMPD3)(AMPD3/901), CF740 conjugate

    产品特性

    Adenosine Monophosphate Deaminase, isoform E (AMPD3) is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. It has 767 amino acids, a MW of ~ 90 kDa, and is assigned an EC 3.5.4.6. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human AMDP3 protein

    亚型

    IgG2b, kappa
  • 应用备注

    Immunohistology formalin-fixed 2-4 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Immunocytochemistry 1-2.0 μg/mL. Immunofluorescence 0.5-1 μg/mL. Flow Cytometry 1-2 μg/million cells in 0.1 mL. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: RBC. Fetal liver, Spleen or Placenta

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

    别名

    Adenosine Monophosphate Deaminase-3

    背景

    Synonyms: AMPD3, Erythrocyte AMP Deaminase, AMP Deaminase 3

    Gene Symbol: AMPD3

    Tissue Expression: Red blood cells

    分子量

    90 kDa

    基因ID

    272

    UniProt

    Q01432
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