YWHAE 抗体 (CF®594)
Quick Overview for YWHAE 抗体 (CF®594) (ABIN7649009)
抗原
See all YWHAE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- 14-3-3E / Tryptophan 5-Monooxygenase(CPTC-YWHAE-1), CF594 conjugate
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产品特性
- 14-3-3E is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length YWHAE protein
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HEK-293 or A-431 cell lines.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- YWHAE (14-3-3 epsilon (YWHAE))
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别名
- 14-3-3E
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背景
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Synonyms: YWHAE, Tyrosine 3-Monooxygenase Activation Protein Epsilon, Tryptophan 5-Monooxygenase Activation Protein Epsilon, epididymis luminal protein 2, Mitochondrial import stimulation factor L subunit, protein kinase C inhibitor protein-1
Gene Symbol: YWHAE
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分子量
- 29.4 kDa
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基因ID
- 7531
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UniProt
- P62268
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途径
- Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
抗原
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