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YWHAE 抗体 (CF®488A)

This anti-YWHAE antibody is a 小鼠 单克隆 antibody detecting YWHAE in WB, IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7649008
发货至: 中国

Quick Overview for YWHAE 抗体 (CF®488A) (ABIN7649008)

抗原

See all YWHAE 抗体
YWHAE (14-3-3 epsilon (YWHAE))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This YWHAE antibody is conjugated to CF®488A

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

CPTC-YWHAE-1
  • 原理

    14-3-3E / Tryptophan 5-Monooxygenase(CPTC-YWHAE-1), CF488A conjugate

    产品特性

    14-3-3E is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human full-length YWHAE protein

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HEK-293 or A-431 cell lines.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    YWHAE (14-3-3 epsilon (YWHAE))

    别名

    14-3-3E

    背景

    Synonyms: YWHAE, Tyrosine 3-Monooxygenase Activation Protein Epsilon, Tryptophan 5-Monooxygenase Activation Protein Epsilon, epididymis luminal protein 2, Mitochondrial import stimulation factor L subunit, protein kinase C inhibitor protein-1

    Gene Symbol: YWHAE

    分子量

    29.4 kDa

    基因ID

    7531

    UniProt

    P62268

    途径

    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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