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APCDD1 抗体 (FITC)

The FITC-conjugated 兔 多克隆 anti-APCDD1 antibody (ABIN731415) specifically detects APCDD1 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN731415
发货至: 中国
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Quick Overview for APCDD1 抗体 (FITC) (ABIN731415)

抗原

See all APCDD1 抗体
APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))

适用

  • 37
  • 15
  • 12
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 36
  • 3
  • 2

克隆类型

  • 35
  • 2
  • 1
多克隆

标记

  • 13
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APCDD1 antibody is conjugated to FITC

应用范围

  • 26
  • 11
  • 10
  • 4
  • 2
Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human APCDD1

    亚型

    IgG
  • 应用备注

    IF(IHC-P)(1:50-200)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))

    别名

    Apcdd1

    背景

    Synonyms: adenomatosio polyposis coli down-regulated 1, Adenomatosis polyposis coli down regulated 1, Adenomatosis polyposis coli down regulated 1 protein, APCDD 1, B7323, DRAPC1, FP7019, Protein APCDD1, APCD1_HUMAN.

    Background: APCDD1 is a novel protein that has been shown to be a target of Wnt/beta catenin signaling pathway in cancer cell lines. APCDD1 is overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1 mutated Wilms tumors.[FUNCTION] Probably plays a role in colorectal tumorigenesis. May be a developmental target gene of the Wnt/Beta-catenin pathway.[SUBCELLULAR LOCATION] Membrane, Single-pass type I membrane protein (Potential). [TISSUE SPECIFICITY] Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. [INDUCTION] Transcriptionally regulated by the CTNNB1/TF7L2complex.

    基因ID

    147495
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