PFN1 抗体 (AA 41-140)
Quick Overview for PFN1 抗体 (AA 41-140) (ABIN731288)
抗原
See all PFN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-140
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Profilin 1
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PFN1 (Profilin 1 (PFN1))
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别名
- Profilin 1
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背景
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Synonyms: ALS18, Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1
Background: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
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基因ID
- 5216
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UniProt
- P07737
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途径
- Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
抗原
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