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BMP2 抗体 (AA 283-365)

This anti-BMP2 antibody is a 兔 多克隆 antibody detecting BMP2 in WB, ELISA, IHC (p), IF (p), IF (cc) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠, 兔 和 绵羊. This Primary Antibody has been cited in 12+ publications.
产品编号 ABIN730903
发货至: 中国

Quick Overview for BMP2 抗体 (AA 283-365) (ABIN730903)

抗原

See all BMP2 抗体
BMP2 (Bone Morphogenetic Protein 2 (BMP2))

适用

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人, 小鼠, 大鼠, 兔, 绵羊

宿主

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克隆类型

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多克隆

标记

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This BMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 283-365

    交叉反应

    人, 小鼠, 兔, 大鼠, 绵羊

    预测反应

    Dog,Cow,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human BMP2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Wu, Jiang, Feng, Jiang, Cheng: "Negative Pressure Therapy in the Regeneration of the Sciatic Nerve Using Vacuum - Assisted Closure in a Rabbit Model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 1027-1033, (2018) (PubMed).

    Zhang, Wang, Shi, Wang, Lai, Yang, Chen, Yang: "Combination of simvastatin, calcium silicate/gypsum, and gelatin and bone regeneration in rabbit calvarial defects." in: Scientific reports, Vol. 6, pp. 23422, (2016) (PubMed).

    Zhou, Yin, Jiang, Niu, Wan, Chen, Shen: "CBX7 deficiency plays a positive role in dentin and alveolar bone development." in: Journal of molecular histology, Vol. 47, Issue 4, pp. 401-11, (2016) (PubMed).

    Sari, Rufaut, Jones, Sinclair: "Characterization of Ovine Dermal Papilla Cell Aggregation." in: International journal of trichology, Vol. 8, Issue 3, pp. 121-9, (2016) (PubMed).

    Naeem, Zhu, Di, Marmiroli, OShaughnessy: "AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation." in: Cell death and differentiation, (2015) (PubMed).

    Wu, Zhou, Hu, Li: "Gene expression of osteogenic factors following gene therapy in mandibular lengthening." in: The Journal of craniofacial surgery, Vol. 26, Issue 2, pp. 378-81, (2015) (PubMed).

    Kishi, Fujihara, Kawaguchi, Yamada, Nakayama, Yamamoto, Fujihara, Hamada, Satomura, Masutani: "PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway." in: International journal of molecular sciences, Vol. 16, Issue 10, pp. 24820-38, (2015) (PubMed).

    Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: "The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 731395, (2014) (PubMed).

    Wu, Chen, Mi, Chen, Wang, Gao: "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." in: International journal of clinical and experimental pathology, Vol. 7, Issue 2, pp. 529-36, (2014) (PubMed).

    Wang, Bi, Zhu, Wu, Wang: "Effects of the antihypertensive drug benidipine on osteoblast function in vitro." in: Experimental and therapeutic medicine, Vol. 7, Issue 3, pp. 649-653, (2014) (PubMed).

    Lescarbeau, Seib, Prewitz, Werner, Kaplan: "In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors." in: PLoS ONE, Vol. 7, Issue 8, pp. e40372, (2012) (PubMed).

  • 抗原

    BMP2 (Bone Morphogenetic Protein 2 (BMP2))

    别名

    BMP2

    背景

    Synonyms: BDA2, BMP2A, Bone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A, BMP-2A, BMP2

    Background: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.

    基因ID

    650

    UniProt

    P12643

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
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