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CXCR4 抗体 (AA 201-294) (PE)

This anti-CXCR4 antibody is a 兔 多克隆 antibody detecting CXCR4 in WB 和 FACS. Suitable for 人, 小鼠, 大鼠 和 兔. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN730898
发货至: 中国

Quick Overview for CXCR4 抗体 (AA 201-294) (PE) (ABIN730898)

抗原

See all CXCR4 抗体
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

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人, 小鼠, 大鼠, 兔

宿主

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克隆类型

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多克隆

标记

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This CXCR4 antibody is conjugated to PE

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

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    AA 201-294

    交叉反应

    人, 小鼠, 兔, 大鼠

    预测反应

    Cow

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CXCR4

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Eweida, Flechtenmacher, Sandberg, Schulte, Schmidt, Kneser, Harhaus: "Systemically injected bone marrow mononuclear cells specifically home to axially vascularized tissue engineering constructs." in: PloS one, Vol. 17, Issue 8, pp. e0272697, (2022) (PubMed).

    Li, Shen, Miao, Luan, Sun, Qiu: "Co-expression of uPAR and CXCR4 promotes tumor growth and metastasis in small cell lung cancer." in: International journal of clinical and experimental pathology, Vol. 7, Issue 7, pp. 3771-80, (2014) (PubMed).

  • 抗原

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    别名

    CXCR4

    背景

    Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, Lipopolysaccharide-associated protein 3, LAP-3, LPS-associated protein 3, NPYRL, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD184, CXCR4

    Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

    基因ID

    7852

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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