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CXCR4 抗体 (AA 201-294)

Name: CXCR4 抗体 (AA 201-294)
SKU: ABIN730888
Availability: OutOfStock

This anti-CXCR4 antibody is a 兔多克隆 antibody detecting CXCR4 in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠和兔. This Primary Antibody has been cited in 16+ publications.

Mouse lung lysates probed with Anti-CXCR4 Polyclonal Antibody at 1:5000 for 90 min at 37˚C. (CXCR4 抗体 (AA 201-294))

L1 rat brain lysates L2 rat kidney lysates probed with Anti- CD184/CXCR4 Polyclonal Antibody, Unconjugated (ABIN730888) at 1:200 overnight at 4 °C. (CXCR4 抗体 (AA 201-294))

SDS

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-CD184/CXCR4 Polyclonal Antibody (ABIN730888), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (CXCR4 抗体 (AA 201-294))

IHC

Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-CD184/CXCR4 Polyclonal Antibody , Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (CXCR4 抗体 (AA 201-294))

8 images

(16 references)

产品编号 ABIN730888

发货至: 中国

Quick Overview for CXCR4 抗体 (AA 201-294) (ABIN730888)

抗原

See all CXCR4 抗体

CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

人, 小鼠, 大鼠, 兔

宿主

兔

克隆类型

多克隆

标记

This CXCR4 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

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AA 201-294

交叉反应

人, 小鼠, 兔, 大鼠

预测反应

Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CXCR4

亚型

IgG
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibody
CXCR4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 262-352) antibody
CXCR4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (N-Term) antibody
CXCR4 适用: 人, 小鼠, 兔, Pig, 马 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 14-40) antibody
CXCR4 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-356) antibody
CXCR4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (C-Term) antibody
CXCR4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibody
CXCR4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F8 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) antibody (PE)
CXCR4 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 12G5 PE

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 2-15), (Extracellular) antibody
CXCR4 适用: 人 WB, IHC, FACS, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (C-Term) antibody
CXCR4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Sha, Yang, Lv: "MGF E peptide improves anterior cruciate ligament repair by inhibiting hypoxia-induced cell apoptosis and accelerating angiogenesis." in: Journal of cellular physiology, Vol. 234, Issue 6, pp. 8846-8861, (2019) (PubMed).

Zhuang, Li, Huang, Lei, Yan, Li, Sidhu, Cheng, Yan, Miao, Zhao, Hua: "Reelin regulates male mouse reproductive capacity via the sertoli cells." in: Journal of cellular biochemistry, (2018) (PubMed).

Ochi, Chen, Schulte, Leng, Moeckel, Piecychna, Averdunk, Stoppe, Bucala, Moeckel: "MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms." in: American journal of physiology. Renal physiology, Vol. 313, Issue 3, pp. F767-F780, (2017) (PubMed).

Aerbajinai, Liu, Zhu, Kumkhaek, Chin, Rodgers: "Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin." in: The Journal of biological chemistry, Vol. 291, Issue 16, pp. 8549-64, (2016) (PubMed).

Wang, Chen, Tang, Jiang, Ji: "AMD3100 Attenuates Matrix Metalloprotease-3 and -9 Expressions and Prevents Cartilage Degradation in a Monosodium Iodo-Acetate-Induced Rat Model of Temporomandibular Osteoarthritis." in: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, Vol. 74, Issue 5, pp. 927.e1-927.e13, (2016) (PubMed).

Mori, Matsubara, Matsubara, Uchikura, Hashimoto, Fujioka, Matsumoto: "Stromal Cell-Derived Factor-1? Plays a Crucial Role Based on Neuroprotective Role in Neonatal Brain Injury in Rats." in: International journal of molecular sciences, Vol. 16, Issue 8, pp. 18018-32, (2015) (PubMed).

Mu, Li, Wu, Zheng, Zhai, Li, Song, Wang, Zhu, Li, Hua: "PLZF-Induced Upregulation of CXCR4 Promotes Dairy Goat Male Germline Stem Cell Proliferation by Targeting Mir146a." in: Journal of cellular biochemistry, (2015) (PubMed).

Zhou, Yang, Xin, Zhang, Hu, Zhou, Chen, Chen et al.: "Exendin-4 enhances the migration of adipose-derived stem cells to neonatal rat ventricular cardiomyocyte-derived conditioned medium via the phosphoinositide 3-kinase/Akt-stromal cell-derived ..." in: Molecular medicine reports, (2015) (PubMed).

Zhou, Li, Shi, Xin, Yang, Zhou, Hu, Tian, Wang, Chen: "Effects of Exendin-4 on bone marrow mesenchymal stem cell proliferation, migration and apoptosis in vitro." in: Scientific reports, Vol. 5, pp. 12898, (2015) (PubMed).

Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: "Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 9, Issue 2, pp. 255-64, (2014) (PubMed).

Wu, Liu, Yan, He, Ye, Cheng, Zhu, Wu, Wang, Kong, Xu, Lobie, Zhu, Wu: "B-cell lymphoma 6 protein stimulates oncogenicity of human breast cancer cells." in: BMC cancer, Vol. 14, pp. 418, (2014) (PubMed).

Li, Shen, Miao, Luan, Sun, Qiu: "Co-expression of uPAR and CXCR4 promotes tumor growth and metastasis in small cell lung cancer." in: International journal of clinical and experimental pathology, Vol. 7, Issue 7, pp. 3771-80, (2014) (PubMed).

Lu, Qi, Bo, Liu, Wang, Li: "Expression of CD26 and CXCR4 in prostate carcinoma and its relationship with clinical parameters." in: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, Vol. 18, Issue 8, pp. 647-52, (2013) (PubMed).

Liu, Patzak, Zhang: "CXCR4-overexpressing bone marrow-derived mesenchymal stem cells improve repair of acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 305, Issue 7, pp. F1064-73, (2013) (PubMed).

Zhuo, Jia, Song, Lu, Ding, Wang, Song, Fu, Luo: "The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 19, pp. 5387-98, (2012) (PubMed).

Fontana, Vogt, Hohenstein, Vettermann, Doroshenko, Lammer, Yard, Hoeger: "Impact of Steroids on the Inflammatory Response after Ischemic Acute Kidney Injury in Rats." in: Indian journal of nephrology, Vol. 27, Issue 5, pp. 365-371 (PubMed).
抗原

CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

别名

CXCR4

背景

Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, Lipopolysaccharide-associated protein 3, LAP-3, LPS-associated protein 3, NPYRL, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD184, CXCR4
Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

基因ID

7852

途径

Regulation of Cell Size, CXCR4-mediated Signaling Events