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CBX5 抗体 (pTyr24)

This anti-CBX5 antibody is a 兔 多克隆 antibody detecting CBX5 in WB, ELISA, IHC (p), IF (p), IF (cc) 和 IHC (fro). Suitable for 人 和 Drosophila melanogaster. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN729943
发货至: 中国

Quick Overview for CBX5 抗体 (pTyr24) (ABIN729943)

抗原

See all CBX5 抗体
CBX5 (Chromobox Homolog 5 (CBX5))

适用

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人, Drosophila melanogaster

宿主

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克隆类型

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  • 1
多克隆

标记

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This CBX5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pTyr24

    交叉反应

    交叉反应 (详细)

    Fruit Fly

    预测反应

    Drosophila

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr24

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Terzuoli, Meini, Cucchi, Catalani, Cialdai, Maggi, Giachetti, Ziche, Donnini: "Antagonism of bradykinin B2 receptor prevents inflammatory responses in human endothelial cells by quenching the NF-kB pathway activation." in: PLoS ONE, Vol. 9, Issue 1, pp. e84358, (2014) (PubMed).

  • 抗原

    CBX5 (Chromobox Homolog 5 (CBX5))

    别名

    HP1

    背景

    Synonyms: Heterochromatin protein 1, HP1, Non-histone chromosomal protein C1A9 antigen, CG8409

    Background: HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are requiredfor binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.

    基因ID

    34119
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