MAFA 抗体
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北京 101111
Quick Overview for MAFA 抗体 (ABIN729898)
抗原
See all MAFA 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Mafa
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亚型
- IgG
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anti-Transcription Factor MafA (MAFA) (AA 222-308) antibody
MAFA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Transcription Factor MafA (MAFA) antibodyMAFA 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 222-308) antibodyMAFA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 81-130) antibodyMAFA 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 300-350) antibodyMAFA 适用: 人, 小鼠, 大鼠, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 71-120) antibodyMAFA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 110-159) antibodyMAFA 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (N-Term) antibodyMAFA 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 282-311) antibodyMAFA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 203-231) antibodyMAFA 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MAFA (Transcription Factor MafA (MAFA))
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别名
- Mafa
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背景
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Synonyms: Mafa homolog, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A,Pancreatic beta-cell-specic transcriptional activator,avianV-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA_MOUSE.
Background: Insulin gene expression is regulated by several islet-enriched transcription factors. However, MAFA is the only beta cell-specific activator. MAFA selectively induces endogenous insulin transcription in non-beta cells. MAFA was also first detected in the insulin-producing cells formed during the second and predominant phase of beta cell differentiation, and absent in the few insulin-positive cells found in Nkx6.1(-/-) pancreata, which lack the majority of second-phase beta cells. These results demonstrate that MAFA is a potent insulin activator that is likely to function downstream of Nkx6.1 during islet insulin-producing cell development.
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基因ID
- 389692
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途径
- Hormone Transport
抗原
-
