PDX1 抗体 (AA 188-284) (Cy7)
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- 抗原 See all PDX1 抗体
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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抗原表位
- AA 188-284
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适用
- 大鼠, 山羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDX1 antibody is conjugated to Cy7
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 山羊, 大鼠
- 预测反应
- Human,Mouse,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from mouse PDX1
- 亚型
- IgG
- Top Product
- Discover our top product PDX1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- 别名
- PDX1 (PDX1 产品)
- 背景
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Synonyms: Ipf1, IDX-1, IPF-1, Mody4, STF-1, pdx-1, Pancreas/duodenum homeobox protein 1, Insulin promoter factor 1, Islet/duodenum homeobox 1, Somatostatin-transactivating factor 1, Pdx1
Background: Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
- 基因ID
- 18609
- UniProt
- P52946
- 途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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