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PAR1 抗体 (AA 251-350)

Name: PAR1 抗体 (AA 251-350)
SKU: ABIN728743
Availability: OutOfStock

This anti-PAR1 antibody is a 兔多克隆 antibody detecting PAR1 in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 大鼠和小鼠. This Primary Antibody has been cited in 5+ publications.

At two weeks upon injury, brain thrombin activity and concentration are similar between mTBI exposed animals and controls. (PAR1 抗体 (AA 251-350))

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-PAR-1 Polyclonal Antibody (ABIN728743), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (PAR1 抗体 (AA 251-350))

IHC

L1 rat heart, L2 rat brain lysates probed (ABIN728743) at 1:200 in 4 °C. (PAR1 抗体 (AA 251-350))

SDS

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-PAR-1 Polyclonal Antibody , Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (PAR1 抗体 (AA 251-350))

IHC (p)

4 images

(5 references)

产品编号 ABIN728743

发货至: 中国

Quick Overview for PAR1 抗体 (AA 251-350) (ABIN728743)

抗原

See all PAR1 (F2R) 抗体

PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

适用

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

This PAR1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

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AA 251-350

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human PAR1

亚型

IgG
anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-102) antibody
F2R 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2C5 unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (N-Term) antibody
F2R 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-176) antibody
F2R 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 5E2E6 unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 61-76), (Extracellular) antibody
F2R 适用: 人 WB, IHC, FACS, IF, LCI, IC 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 42-102) antibody
F2R 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 1-425) antibody
F2R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (N-Term) antibody
F2R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (Internal Region) antibody
Verified F2R 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 267-316) antibody
F2R 适用: 人, 大鼠, 小鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated

anti-Coagulation Factor II (thrombin) Receptor (F2R) (N-Term) antibody
F2R 适用: 人 ELISA, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal ATAP2 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Posthuma, Posma, Schep, Bender, van Oerle, van der Wal, Ten Cate, Spronk: "Protease-activated receptors are potential regulators in the development of arterial endofibrosis in high-performance athletes." in: Journal of vascular surgery, Vol. 69, Issue 4, pp. 1243-1250, (2019) (PubMed).

Ben Shimon, Zeimer, Shavit Stein, Artan-Furman, Harnof, Chapman, Eisenkraft, Pick, Maggio: "Recovery from trauma induced amnesia correlates with normalization of thrombin activity in the mouse hippocampus." in: PLoS ONE, Vol. 12, Issue 11, pp. e0188524, (2017) (PubMed).

Fan, Chen, Ni, Wang, Sun, Chen, Zheng: "Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers." in: OncoTargets and therapy, Vol. 8, pp. 1619-26, (2015) (PubMed).

Acton, Miles: "Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine." in: PLoS ONE, Vol. 10, Issue 8, pp. e0134488, (2015) (PubMed).

Liu, Xie, Luo, Chen, Zhou, Xia, Chen, Zhou, Cao, Cao, Zhou: "Identification of FLOT2 as a novel target for microRNA-34a in melanoma." in: Journal of cancer research and clinical oncology, (2014) (PubMed).
抗原

PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

别名

Thrombin receptor

背景

Synonyms: TR, HTR, CF2R, PAR1, PAR-1, Proteinase-activated receptor 1, Coagulation factor II receptor, Thrombin receptor, F2R
Background: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

基因ID

2149

UniProt

P25116

途径

Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus