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MUC16 抗体 (Biotin)

This anti-MUC16 antibody is a Human Chimeric antibody detecting MUC16 in FACS. Suitable for 人.
产品编号 ABIN7608320
发货至: 中国

Quick Overview for MUC16 抗体 (Biotin) (ABIN7608320)

抗原

See all MUC16 (CA125) 抗体
MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

适用

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宿主

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Human, 兔

克隆类型

  • 87
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Chimeric

标记

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This MUC16 antibody is conjugated to Biotin

应用范围

  • 73
  • 52
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  • 16
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Flow Cytometry (FACS)

克隆位点

3B11
  • 原理

    Biotinylated Anti-MUC16 antibody(3B11), IgG1 Chimeric mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt 1/100

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 26 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -98°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

    别名

    MUC16

    背景

    This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. [provided by RefSeq, May 2017]

    UniProt

    Q8WXI7
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