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IL12RB1 抗体

IL12RB1 适用: 人 FACS 宿主: Human, 兔 Chimeric 1F11 unconjugated
产品编号 ABIN7607997
发货至: 中国
  • 抗原 See all IL12RB1 抗体
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    适用
    • 32
    • 21
    • 21
    宿主
    • 47
    • 3
    • 2
    Human, 兔
    克隆类型
    • 50
    • 2
    Chimeric
    标记
    • 21
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL12RB1 antibody is un-conjugated
    应用范围
    • 38
    • 12
    • 12
    • 12
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    原理
    Anti-IL12RB1 antibody(1F11), IgG1 Chimeric mAb
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    克隆位点
    1F11
    亚型
    IgG1
    Top Product
    Discover our top product IL12RB1 Primary Antibody
  • 应用备注
    Flow Cyt 1/100
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    别名
    IL12RB1 (IL12RB1 产品)
    背景
    The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
    UniProt
    P42701
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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