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Calreticulin 抗体

The 兔 单克隆 anti-Calreticulin antibody is suitable to detect Calreticulin in samples from 人. It has been validated for ELISA.
产品编号 ABIN7607951
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Calreticulin 抗体 (ABIN7607951)

抗原

See all Calreticulin (CALR) 抗体
Calreticulin (CALR)

适用

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宿主

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克隆类型

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单克隆

标记

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This Calreticulin antibody is un-conjugated

应用范围

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ELISA

克隆位点

1A8
  • 原理

    Anti-CALR antibody(1A8), Rabbit mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
  • 应用备注

    ELISA 1/5000-10000

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please see Certificate of Analysis for specific instructions of reconstitution.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    Calreticulin (CALR)

    别名

    CALR

    背景

    Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]

    UniProt

    P27797

    途径

    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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