SMURF2 抗体
Quick Overview for SMURF2 抗体 (ABIN7606330)
抗原
See all SMURF2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-SMURF 2 Rabbit Monoclonal Antibody
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产品特性
- Anti-SMURF 2 Rabbit Monoclonal Antibody (ABIN7606330). Tested in WB application. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human SMURF 2 E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation.
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亚型
- IgG
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应用备注
- WB 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))
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别名
- SMURF2
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背景
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Synonyms: Neurogenic locus notch homolog protein 4,Notch 4,hNotch4,Notch 4 extracellular truncation,Notch 4 intracellular domain,NOTCH4,INT3,
Tissue Specificity: Highly expressed in the heart, moderately in the lung and placenta and at low levels in the liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow and fetal liver. No expression was seen in adult brain or peripheral blood leukocytes.
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分子量
- 41 kDa
抗原
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