Cyclin C 抗体 (AA 23-100)
Quick Overview for Cyclin C 抗体 (AA 23-100) (ABIN727250)
抗原
See all Cyclin C (CCNC) 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 23-100
- 
                                            交叉反应
- 人
- 
                                            预测反应
- Mouse,Rat
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human Cyclin C
- 
                                            亚型
- IgG
 
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                                            应用备注
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                        WB 1:300-5000
 ELISA 1:500-1000
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 
                                            有效期
- 12 months
 
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    - Cyclin C (CCNC)
- 
                                            别名
- Cyclin C
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                                            背景
- 
                        Synonyms: CycC, Cyclin-C, SRB11 homolog, hSRB11, CCNC Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. 
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                                            基因ID
- 892
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                                            UniProt
- P24863
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                                            途径
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
 抗原
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