PDPK1 抗体
Quick Overview for PDPK1 抗体 (ABIN7605897)
抗原
See all PDPK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
 - Anti-PDK1 Monoclonal Antibody
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产品特性
 - Anti-PDK1 Monoclonal Antibody (ABIN7605897). Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
 - Affinity-chromatography
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免疫原
 - A synthesized peptide derived from human PDK1 Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
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亚型
 - IgG
 
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应用备注
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                        WB 1:500-1:2000
IP 1:50 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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溶解方式
 - Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
 - Lot specific
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缓冲液
 - Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
 
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- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
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别名
 - PDK1
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背景
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Synonyms: Actin, cytoplasmic 1,Beta-actin,Actin, cytoplasmic 1, N-terminally processed,ACTB,
Tissue Specificity: Preferentially expressed in melanomas. Some expression was found in dysplastic nevi. Not found in normal tissues nor in carcinomas. Normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth.
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分子量
 - 42 kDa
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UniProt
 - Q15118
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途径
 - PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
 
抗原
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