LCK 抗体
Quick Overview for LCK 抗体 (ABIN7605414)
抗原
See all LCK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Lck Monoclonal Antibody
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产品特性
- Anti-Lck Monoclonal Antibody (ABIN7605414). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Lck The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells. Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects.
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亚型
- IgG
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应用备注
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WB 1:500-1:1000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:80
FC 1:20 -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
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别名
- LCK
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背景
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Synonyms: Prolyl endopeptidase FAP ,3.4.21.26 ,170 kDa melanoma membrane-bound gelatinase ,Dipeptidyl peptidase FAP ,3.4.14.5 ,Fibroblast activation protein alpha ,FAPalpha ,Gelatine degradation protease FAP ,3.4.21.- ,Integral membrane serine protease ,Post-proline cleaving enzyme ,Serine integral membrane protease ,SIMP ,Surface-expressed protease ,Seprase ,Antiplasmin-cleaving enzyme FAP, soluble form ,APCE ,3.4.14.5 ,3.4.21.- ,3.4.21.26 ,FAP ,
Tissue Specificity: Expressed in adipose tissue. Expressed in the dermal fibroblasts in the fetal skin. Expressed in the granulation tissue of healing wounds and on reactive stromal fibroblast in epithelial cancers. Expressed in activated fibroblast-like synoviocytes from inflamed synovial tissues. Expressed in activated hepatic stellate cells (HSC) and myofibroblasts from cirrhotic liver, but not detected in normal liver. Expressed in glioma cells (at protein level). Expressed in glioblastomas and glioma cells. Isoform 1 and isoform 2 are expressed in melanoma, carcinoma and fibroblast cell lines. .
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分子量
- 11 kDa
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UniProt
- P06239
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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