GNAQ 抗体
Quick Overview for GNAQ 抗体 (ABIN7605002)
抗原
See all GNAQ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-GNAQ Rabbit Monoclonal Antibody
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产品特性
- Anti-GNAQ Rabbit Monoclonal Antibody (ABIN7605002). Tested in WB application. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human GNAQ
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亚型
- IgG
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
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别名
- GNAQ
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背景
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Synonyms: Protein lin-28 homolog B,Lin-28B,LIN28B,CSDD2,
Tissue Specificity: Expressed at high levels in the placenta and, at mucher lower, in testis and fetal liver (PubMed:16971064). Isoform 1 is only detected in placenta and in moderately and poorly differentiated hepatocellular carcinoma cells (at protein level). Isoform 2 is detected in fetal liver, non-tumor liver tissues, as well as well-differentiated tumor tissues (at protein level). Tends to be up-regulated in triple-negative (ER-,PR-,HER2-) breast tumors, as well as in liver, ovarian, and thyroid carcinomas (PubMed:22118463). .
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分子量
- 42 kDa
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UniProt
- P50148
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途径
- JAK/STAT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
抗原
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