Geminin 抗体
Quick Overview for Geminin 抗体 (ABIN7604960)
抗原
See all Geminin (GMNN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Geminin Monoclonal Antibody
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产品特性
- Anti-Geminin Monoclonal Antibody (ABIN7604960). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Geminin Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
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亚型
- IgG
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应用备注
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WB 1:500-1:1000
IHC 1:50-1:200
ICC/IF 1:50-1:200 -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
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别名
- GMNN
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背景
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Synonyms: Hyaluronan and proteoglycan link protein 1,Cartilage-linking protein 1,Cartilage-link protein,Proteoglycan link protein,HAPLN1,CRTL1,
Tissue Specificity: Widely expressed. Weakly expressed in the brain. .
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分子量
- 63 kDa
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UniProt
- O75496
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途径
- EGFR Signaling Pathway, DNA Replication
抗原
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