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EIF4E 抗体 (pSer209)

This anti-EIF4E antibody is a 兔 单克隆 antibody detecting EIF4E in WB, IHC, FACS 和 IP. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7603287
发货至: 中国

Quick Overview for EIF4E 抗体 (pSer209) (ABIN7603287)

抗原

See all EIF4E 抗体
EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

适用

  • 124
  • 62
  • 50
  • 19
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
人, 大鼠, 小鼠

宿主

  • 108
  • 15
  • 2

克隆类型

  • 99
  • 26
单克隆

标记

  • 59
  • 9
  • 8
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This EIF4E antibody is un-conjugated

应用范围

  • 98
  • 52
  • 43
  • 27
  • 27
  • 26
  • 16
  • 16
  • 15
  • 14
  • 7
  • 6
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

AFHI-5
  • 抗原表位

    • 39
    • 15
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer209

    原理

    Anti-EIF4E Monoclonal Antibody

    产品特性

    Anti-EIF4E Monoclonal Antibody (ABIN7603287). Tested in WB, IHC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human EIF4E eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.

    亚型

    IgG
  • 应用备注

    WB 1:100-1:5000
    IHC 1:100-1:500
    IP 1:30
    FC 1:40

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    浓度

    Lot specific

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • 抗原

    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

    别名

    EIF4E

    背景

    Synonyms: Transcriptional repressor CTCF,11-zinc finger protein,CCCTC-binding factor,CTCFL paralog,CTCF,

    Tissue Specificity: Ubiquitous. Absent in primary spermatocytes. .

    分子量

    25 kDa

    UniProt

    P06730

    途径

    BCR Signaling
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