TRIM25 抗体 (N-Term)
Quick Overview for TRIM25 抗体 (N-Term) (ABIN7603254)
抗原
See all TRIM25 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Anti-TRIM25 Monoclonal Antibody
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产品特性
- Anti-TRIM25 Monoclonal Antibody (ABIN7603254). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human TRIM25 Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.
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亚型
- IgG
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应用备注
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WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:100-1:500
IP 1:50
FC 1:60 -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
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别名
- TRIM25
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背景
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Synonyms: Peptidyl-prolyl cis-trans isomerase B,PPIase B,5.2.1.8,CYP-S1,Cyclophilin B,Rotamase B,S-cyclophilin,SCYLP,PPIB,CYPB,
Tissue Specificity: Expressed in brain in the thalamus, in fetal and adult lung and in placenta. .
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分子量
- 71 kDa
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UniProt
- Q14258
抗原
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