UCP3 抗体 (N-Term)
Quick Overview for UCP3 抗体 (N-Term) (ABIN7603247)
抗原
See all UCP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-UCP3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-UCP3 Antibody Picoband® (ABIN7603247). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human UCP3, which shares 73.1% and 76.9% amino acid (aa) sequence identity with mouse and rat UCP3, respectively.
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亚型
- IgG
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anti-Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (AA 33-76) antibody
UCP3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (AA 1-113), (AA 217-312) antibodyUCP3 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6B8C6 unconjugated
anti-Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (AA 1-110) antibodyUCP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (C-Term) antibodyUCP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (C-Term) antibodyUCP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (C-Term) antibodyUCP3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (AA 125-175) antibodyUCP3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
1. Argyropoulos, G., Brown, A. M., Willi, S. M., Zhu, J., He, Y., Reitman, M., Gevao, S. M., Spruill, I., Garvey, W. T. Effects of mutations in the human uncoupling protein 3 gene on the respiratory quotient and fat oxidation in severe obesity and type 2 diabetes. J. Clin. Invest. 102: 1345-1351, 1998. 2. Boss, O., Giacobino, J.-P., Muzzin, P. Genomic structure of uncoupling protein-3 (UCP3) and its assignment to chromosome 11q13. Genomics 47: 425-426, 1998. 3. Boss, O., Samec, S., Paoloni-Giacobino, A., Rossier, C., Dulloo, A., Seydoux, J., Muzzin, P., Giacobino, J.-P. Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett. 408: 39-42, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))
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别名
- UCP3
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背景
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Synonyms: Ubiquitin-like-conjugating enzyme ATG3,6.3.2.-,Autophagy-related protein 3,APG3-like,hApg3,Protein PC3-96,ATG3,APG3, APG3L,
Tissue Specificity: Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta. .
Background: Mitochondrial uncoupling protein 3 is a protein that in humans is encoded by the UCP3 gene. Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression, this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.
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分子量
- 30 kDa
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基因ID
- 7352
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UniProt
- P55916
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途径
- Proton Transport
抗原
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