TPM2 抗体 (N-Term)
Quick Overview for TPM2 抗体 (N-Term) (ABIN7603245)
抗原
See all TPM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Tropomyosin 2/TPM2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Tropomyosin 2/TPM2 Antibody Picoband® (ABIN7603245). Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Tropomyosin 2/TPM2, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Tropomyosin-2 (TPM2) antibody
TPM2 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin-2 (TPM2) antibodyTPM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin-2 (TPM2) (AA 1-284) antibodyTPM2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C8 unconjugated
anti-Tropomyosin-2 (TPM2) (C-Term) antibodyTPM2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 斑马鱼, 豚鼠, 马, Pig, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin-2 (TPM2) (C-Term) antibodyTPM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin-2 (TPM2) (C-Term) antibodyTPM2 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, 兔, 斑马鱼, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin-2 (TPM2) antibodyTPM2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin-2 (TPM2) (AA 11-130) antibodyTPM2 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin-2 (TPM2) (AA 1-284) antibodyTPM2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
1. Bamshad, M., Watkins, W. S., Zenger, R. K., Bohnsack, J. F., Carey, J. C., Otterud, B., Krakowiak, P. A., Robertson, M., Jorde, L. B. A gene for distal arthrogryposis type I maps to the pericentromeric region of chromosome 9. Am. J. Hum. Genet. 55: 1153-1158, 1994. 2. Clarke, N. F., Domazetovska, A., Waddell, L., Kornberg, A., McLean, C., North, K. N. Cap disease due to mutation of the beta-tropomyosin gene (TPM2). Neuromusc. Disord. 19: 348-351, 2009. 3. Davidson, A. E., Siddiqui, F. M., Lopez, M. A., Lunt, P., Carlson, H. A., Moore, B. E., Love, S., Born, D. E., Roper, H., Majumdar, A., Jayadev, S., Underhill, H. R., and 14 others. Novel deletion of lysine 7 expands the clinical, histopathological and genetic spectrum of TPM2-related myopathies. Brain 136: 508-521, 2013. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TPM2 (Tropomyosin-2 (TPM2))
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别名
- TPM2
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背景
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Synonyms: TNF receptor-associated factor 5,RING finger protein 84,TRAF5,RNF84,
Tissue Specificity: Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
Background: β-Tropomyosin, also known as tropomyosin beta chain is a protein that in humans is encoded by the TPM2 gene. This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 38 kDa
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基因ID
- 7169
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UniProt
- P07951
抗原
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