TNNI1 抗体 (N-Term)
Quick Overview for TNNI1 抗体 (N-Term) (ABIN7603242)
抗原
See all TNNI1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- Anti-TNNI1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-TNNI1 Antibody Picoband® (ABIN7603242). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human TNNI1, which shares 94.7% amino acid (aa) sequence identity with mouse and rat TNNI1.
-
亚型
- IgG
-
-
anti-Slow Skeletal Troponin I (TNNI1) (AA 1-187) antibody
TNNI1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (N-Term) antibodyTNNI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (AA 142-187) antibodyTNNI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (AA 1-187) antibodyTNNI1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (AA 2-173) antibodyTNNI1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (AA 1-187) antibodyTNNI1 适用: 大鼠 WB 宿主: 小鼠 Monoclonal 1203# unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (AA 1-187) antibodyTNNI1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (AA 111-160) antibodyTNNI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, 斑马鱼, Pig, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (N-Term) antibodyVerified TNNI1 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Slow Skeletal Troponin I (TNNI1) (AA 1-187) antibodyTNNI1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. Guenet, J.-L., Simon-Chazottes, D., Gravel, M., Hastings, K. E. M., Schiaffino, S. Cardiac and skeletal muscle troponin I isoforms are encoded by a dispersed gene family on mouse chromosomes 1 and 7. Mammalian Genome 7: 13-15, 1996. 2. Tiso, N., Rampoldi, L., Pallavicini, A., Zimbello, R., Pandolfo, D., Valle, G., Lanfranchi, G., Danieli, G. A. Fine mapping of five human skeletal muscle genes: alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast. Biochem. Biophys. Res. Commun. 230: 347-350, 1997. 3. Wade, R., Eddy, R., Shows, T. B., Kedes, L. cDNA sequence, tissue-specific expression, and chromosomal mapping of the human slow-twitch skeletal muscle isoform of troponin I. Genomics 7: 346-357, 1990. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- TNNI1 (Slow Skeletal Troponin I (TNNI1))
-
别名
- TNNI1
-
背景
-
Synonyms: Ribosome-binding protein 1, 180 kDa ribosome receptor homolog, RRp, ES/130-related protein, Ribosome receptor protein, RRBP1, KIAA1398
Tissue Specificity: Expressed in kidney.
Background: Troponin I, slow skeletal muscle is a protein that in humans is encoded by the TNNI1 gene. Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
-
分子量
- 22 kDa
-
基因ID
- 7135
-
UniProt
- P19237
抗原
-
