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MAVS 抗体 (N-Term)

This anti-MAVS antibody is a 兔 多克隆 antibody detecting MAVS in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7603227
发货至: 中国

Quick Overview for MAVS 抗体 (N-Term) (ABIN7603227)

抗原

See all MAVS 抗体
MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

适用

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宿主

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克隆类型

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多克隆

标记

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This MAVS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    原理

    Anti-MAVS Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MAVS Antibody Picoband® (ABIN7603227). Tested in IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at N-terminus of human MAVS.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    1. Seth RB, Sun L, Ea CK, Chen ZJ (Sep 2005). "Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3". Cell. 122 (5): 669-82. 2. Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB (Sep 2005). "VISA is an adapter protein required for virus-triggered IFN-beta signaling". Mol Cell. 19 (6): 727-40.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

    别名

    MAVS

    背景

    Synonyms: Mitochondrial antiviral-signaling protein,MAVS,CARD adapter inducing interferon beta,Cardif,Interferon beta promoter stimulator protein 1,IPS-1,Putative NF-kappa-B-activating protein 031N,Virus-induced-signaling adapter,VISA,MAVS,IPS1, KIAA1271, VISA,

    Tissue Specificity: Present in T-cells, monocytes, epithelial cells and hepatocytes (at protein level). Ubiquitously expressed, with highest levels in heart, skeletal muscle, liver, placenta and peripheral blood leukocytes. .

    Background: Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity.

    分子量

    75 kDa

    基因ID

    57506

    UniProt

    Q7Z434

    途径

    Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
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