HAT1 抗体 (N-Term)
Quick Overview for HAT1 抗体 (N-Term) (ABIN7603224)
抗原
See all HAT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- Anti-KAT1/HAT1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-KAT1/HAT1 Antibody Picoband® (ABIN7603224). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at N-terminus of human HAT1, identical to the related mouse and rat sequences.
-
亚型
- IgG
-
-
anti-Histone Acetyltransferase 1 (HAT1) antibody
HAT1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 245-419), (Catalytic Subunit) antibodyHAT1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 245-419), (Catalytic Subunit) antibodyHAT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) antibodyHAT1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (C-Term) antibodyHAT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 100-338) antibodyHAT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 389-419), (C-Term) antibodyHAT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5769 unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 331-380) antibodyHAT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Dutnall, R. N., Tafrov, S. T., Sternglanz, R., Ramakrishnan, V. Structure of the histone acetyltransferase Hat1: a paradigm for the GCN5-related N-acetyltransferase superfamily. Cell 94: 427-438, 1998. 2. Verreault, A., Kaufman, P. D., Kobayashi, R., Stillman, B. Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase. Curr. Biol. 8: 96-108, 1998. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- HAT1 (Histone Acetyltransferase 1 (HAT1))
-
别名
- HAT1
-
背景
-
Synonyms: Protocadherin-15, PCDH15, USH1F
Tissue Specificity: Expressed in brain, lung, kidney, spleen and testis. Found also in the inner and outer synaptic layers, and the nerve fiber layer in adult and fetal retinas. Found in the supporting cells, outer sulcus cells and spiral ganglion of fetal cochlea. Expressed in cytotoxic tumor-derived T- and NK-cell lines as well as biopsies of nasal NK/T-cell lymphomas. Not detected in normal or in vitro activated peripheral blood cells, CD4 or CD8 lymphocytes or NK cells. Isoform 3 is expressed in brain, heart, cerebellum and kidney. CD1 isoforms, such as isoform 1, have a limited pattern of expression and is detected in testis, retina and cochlea. CD2 isoforms, such as isoforms 4 and 5, are expressed in heart, kidney, thymus, spleen, testis, retina and cochlea. CD3 isoforms, such as isoform 6, are widely expressed.
Background: Histone acetyltransferase 1, also known as HAT1, is an enzyme that, in humans, is encoded by the HAT1 gene. The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
-
分子量
- 50 kDa
-
基因ID
- 8520
-
UniProt
- O14929
抗原
-
