GAS2 抗体 (N-Term)
Quick Overview for GAS2 抗体 (N-Term) (ABIN7603220)
抗原
See all GAS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-GAS2 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-GAS2 Antibody Picoband® (ABIN7603220). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human GAS2, identical to the related mouse sequences.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Brancolini, C., Bottega, S., Schneider, C. Gas2, a growth arrest-specific protein, is a component of the microfilament network system. J. Cell Biol. 117: 1251-1261, 1992. 2. Collavin, L., Buzzai, M., Saccone, S., Bernard, L., Federico, C., DellaValle, G., Brancolini, C., Schneider, C. cDNA characterization and chromosome mapping of the human GAS2 gene. Genomics 48: 265-269, 1998. 3. Colombo, M. P., Martinotti, A., Howard, T. A., Schneider, C., D'Eustachio, P., Seldin, M. F. Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16. Mammalian Genome 2: 130-134, 1992. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GAS2 (Growth Arrest-Specific 2 (GAS2))
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别名
- GAS2
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背景
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Synonyms: Gap junction gamma-1 protein,Connexin-45,Cx45,Gap junction alpha-7 protein,GJC1,GJA7,
Tissue Specificity: Ubiquitously expressed.
Background: Growth arrest-specific protein 2 is a protein that in humans is encoded by the GAS2 gene. The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants.
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分子量
- 35 kDa
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基因ID
- 2620
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UniProt
- O43903
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途径
- Caspase Cascade in Apoptosis
抗原
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