Ezrin 抗体 (N-Term)
Quick Overview for Ezrin 抗体 (N-Term) (ABIN7603214)
抗原
See all Ezrin (EZR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Ezrin/EZR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Ezrin/EZR Antibody Picoband® (ABIN7603214). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Ezrin/EZR, which shares 85.7% amino acid (aa) sequence identity with mouse and rat EZR.
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亚型
- IgG
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anti-Ezrin (EZR) (AA 292-464) antibody
EZR 适用: 人, 小鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F1A9 unconjugated
anti-Ezrin (EZR) (AA 1-295) antibodyEZR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-586) antibodyEZR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (pTyr478) antibodyEZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-586) antibodyEZR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Ezrin (EZR) antibodyEZR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-Ezrin-1 unconjugated
anti-Ezrin (EZR) (pTyr353) antibodyEZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 350-470) antibodyEZR 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 455-586) antibodyEZR 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-251) antibodyEZR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Allenspach, E. J., Cullinan, P., Tong, J., Tang, Q., Tesciuba, A. G., Cannon, J. L., Takahashi, S. M., Morgan, R., Burkhardt, J. K., Sperling, A. I. ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse. Immunity 15: 739-750, 2001. 2. Bonilha, V. L., Rodriguez-Boulan, E. Polarity and developmental regulation of two PDZ proteins in the retinal pigment epithelium. Invest. Ophthal. Vis. Sci. 42: 3274-3282, 2001. 3. Faure, S., Salazar-Fontana, L. I., Semichon, M., Tybulewicz, V. L. J., Bismuth, G., Trautmann, A., Germain, R. N., Delon, J. ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation. Nature Immun. 5: 272-279, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Ezrin (EZR)
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别名
- EZR
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背景
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Synonyms: Dihydropyrimidine dehydrogenase [NADP (+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPYD
Tissue Specificity: Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
Background: Ezrin also known as cytovillin or villin-2 is a protein that in humans is encoded by the EZR gene. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
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分子量
- 81 kDa
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基因ID
- 7430
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UniProt
- P15311
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途径
- Maintenance of Protein Location
抗原
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