DPYSL2 抗体 (N-Term)
Quick Overview for DPYSL2 抗体 (N-Term) (ABIN7603208)
抗原
See all DPYSL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-CRMP2/DPYSL2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CRMP2/DPYSL2 Antibody Picoband® (ABIN7603208). Tested in IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human CRMP2/DPYSL2, which shares 94.1% amino acid (aa) sequence identity with both mouse and rat CRMP2/DPYSL2.
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亚型
- IgG
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anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 1-572) antibody
DPYSL2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 470-571) antibodyDPYSL2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (C-Term) antibodyDPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) antibodyDPYSL2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 400-500) antibodyKO Validated DPYSL2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (C-Term) antibodyDPYSL2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (Thr509) antibodyDPYSL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 480-529) antibodyDPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 463-492) antibodyDPYSL2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 33CT11-40-3 unconjugated
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 1-100) antibodyDPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Abe, H., Jitsuki, S., Nakajima, W., Murata, Y., Jitsuki-Takahashi, A., Katsuno, Y., Tada, H., Sano, A., Suyama, K., Mochizuki, N., Komori, T., Masuyama, H., Okuda, T., Goshima, Y., Higo, N., Takahashi, T. CRMP2-binding compound, edonerpic maleate, accelerates motor function recovery from brain damage. Science 360: 50-57, 2018. 2. Brittain, J. M., Duarte, D. B., Wilson, S. M., Zhu, W., Ballard, C., Johnson, P. L., Liu, N., Xiong, W., Ripsch, M. S., Wang, Y., Fehrenbacher, J. C., Fitz, S. D., and 20 others. Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca(2+) channel complex. Nature Med. 17: 822-829, 2011. 3. Fukata, Y., Itoh, T. J., Kimura, T., Menager, C., Nishimura, T., Shiromizu, T., Watanabe, H., Inagaki, N., Iwamatsu, A., Hotani, H., Kaibuchi, K. CRMP-2 binds to tubulin heterodimers to promote microtubule assembly. Nature Cell Biol. 4: 583-591, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
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别名
- DPYSL2
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背景
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Synonyms: Talin-1, TLN1, KIAA1027, TLN
Tissue Specificity: Placenta and skin. Predominantly expressed in mammary gland tissue.
Background: Dihydropyrimidinase-related protein 2 is an enzyme that in humans is encoded by the DPYSL2 gene. This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 65 kDa
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基因ID
- 1808
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UniProt
- Q16555
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途径
- Regulation of Cell Size
抗原
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