COX6B1 抗体 (N-Term)
Quick Overview for COX6B1 抗体 (N-Term) (ABIN7603206)
抗原
See all COX6B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-COX6B1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-COX6B1 Antibody Picoband® (ABIN7603206). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human COX6B1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) (AA 1-86) antibody
COX6B1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) antibodyCOX6B1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) (AA 1-86) antibodyCOX6B1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5D3 unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) (AA 1-86) antibodyCOX6B1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) (C-Term) antibodyCOX6B1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) (AA 8-22), (N-Term) antibodyCOX6B1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB48530 unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) (AA 1-86) antibodyCOX6B1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) (AA 1-86) antibodyCOX6B1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D3 unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) antibodyCOX6B1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1) (AA 1-86) antibodyCOX6B1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Abdulhag, U. N., Soiferman, D., Schueler-Furman, O., Miller, C., Shaag, A., Elpeleg, O., Edvardson, S., Saada, A. Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathy. Europ. J. Hum. Genet. 23: 159-164, 2015. 2. Carrero-Valenzuela, R. D., Quan, F., Lightowlers, R., Kennaway, N. G., Litt, M., Forte, M. Human cytochrome c oxidase subunit VIb: characterization and mapping of a multigene family. Gene 102: 229-236, 1991. 3. Massa, V., Fernandez-Vizarra, E., Alshahwan, S., Bakhsh, E., Goffrini, P., Ferrero, I., Mereghetti, P., D'Adamo, P., Gasparini, P., Zeviani, M. Severe infantile encephalomyopathy caused by a mutation in COX6B1, a nucleus-encoded subunit of cytochrome c oxidase. Am. J. Hum. Genet. 82: 1281-1289, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- COX6B1 (Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1))
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别名
- COX6B1
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背景
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Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA
Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.
Background: Cytochrome c oxidase subunit 6B1 is an enzyme that in humans is encoded by the COX6B1 gene. Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.
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分子量
- 12 kDa
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基因ID
- 1340
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UniProt
- P14854
抗原
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