TMBIM1 抗体 (N-Term)
Quick Overview for TMBIM1 抗体 (N-Term) (ABIN7603190)
抗原
See all TMBIM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-TMBIM1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TMBIM1 Antibody Picoband® (ABIN7603190). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human TMBIM1, which shares 87.5% and 93.8% amino acid (aa) sequence identity with mouse and rat TMBIM1, respectively.
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亚型
- IgG
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anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (AA 1-109) antibody
TMBIM1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (C-Term) antibodyTMBIM1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (C-Term) antibodyTMBIM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (C-Term) antibodyTMBIM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (AA 46-95) antibodyTMBIM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (AA 68-97), (N-Term) antibodyTMBIM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32602 unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (N-Term) antibodyTMBIM1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Yoshisue, H., Suzuki, K., Kawabata, A., Ohya, T., Zhao, H., Sakurada, K., Taba, Y., Sasguri, T., Sakai, N., Yamashita, S., Matsuzawa, Y., Nojima, H. Large scale isolation of non-uniform shear stress-responsive genes from cultured endothelial cells through the preparation of a subtracted cDNA library. Atherosclerosis 162: 323-334, 2002. 2. Zhao, H., Ito, A., Kimura, S. H., Yabuta, N., Sakai, N., Ikawa, M., Okabe, M., Matsuzawa, Y., Yamashita, S., Nojima, H. RECS1 deficiency in mice induces susceptibility to cystic medial degeneration. Genes Genet. Syst. 81: 41-50, 2006. 3. Zhao, H., Ito, A., Sakai, N., Matsuzawa, Y., Yamashita, S., Nojima, H. RECS1 is a negative regulator of matrix metalloproteinase-9 production and aged RECS1 knockout mice are prone to aortic dilation. Circ. J. 70: 615-624, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))
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别名
- TMBIM1
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背景
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Synonyms: E3 ubiquitin-protein ligase RNF169, RING finger protein 169, RING-type E3 ubiquitin transferase RNF169, RNF169, KIAA1991
Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.
Background: Transmembrane BAX inhibitor motif-containing protein 1 is a protein that in humans is encoded by the TMBIM1 gene. TMBIM1 is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation. A drosophila homolog of this protein (dNMDA1 with 40 % homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.
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分子量
- 35 kDa
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基因ID
- 64114
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UniProt
- Q969X1
抗原
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