Reticulon 4 抗体 (N-Term)
Quick Overview for Reticulon 4 抗体 (N-Term) (ABIN7603185)
抗原
See all Reticulon 4 (RTN4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Nogo A/RTN4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Nogo A/RTN4 Antibody Picoband® (ABIN7603185). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Nogo A/RTN4.
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亚型
- IgG
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anti-Reticulon 4 (RTN4) (AA 501-515) antibody
RTN4 适用: 人, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 14-30) antibodyRTN4 适用: 人, 小鼠, 大鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 301-400) antibodyRTN4 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 251-357) antibodyRTN4 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 28-58) antibodyRTN4 适用: 人 WB 宿主: 兔 Polyclonal RB54371 unconjugated
anti-Reticulon 4 (RTN4) (AA 81-130) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴, 马, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 254-303) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴, 马, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Center) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Middle Region) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 马, 豚鼠, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, human
Immunocytochemistry/Immunofluorescence, 4 μg/mL, Human
Immunofluorescence, 4 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Prinjha R, Moore SE, Vinson M, Blake S, Morrow R, Christie G, Michalovich D, Simmons DL, Walsh FS.Inhibitor of neurite outgrowth in humans. Nature. 2000 Jan 27, 403(6768):383-4. 2. Chen MS, Huber AB, van der Haar ME, Frank M, Schnell L, Spillmann AA, Christ F, Schwab ME.Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature. 2000 Jan 27, 403(6768):434-9. 3. GrandPre T, Nakamura F, Vartanian T, Strittmatter SM.Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. Nature. 2000 Jan 27, 403(6768):439-44. 4. Fournier AE, GrandPre T, Strittmatter SM. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature. 2001 Jan 18, 409(6818):341-6. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Reticulon 4 (RTN4)
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别名
- RTN4
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背景
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Synonyms: Bone morphogenetic protein 15, BMP-15, Growth/differentiation factor 9B, GDF-9B, BMP15, GDF9B
Background: Human neurite outgrowth inhibitor (NOGO) cDNAs encodes 3 splice variants: NOGOA, NOGOB and NOGOC. The longest cDNA, designated NOGOA, has an open reading frame of 1192 amino acids. It is a potent inhibitor of neurite growth and an IN-1 antigen produced by oligodendrocytes, and may allow the generation of new reagents to enhance CNS regeneration and plasticity. Nogo-A, a member of the Reticulon family, is expressed by oligodendrocytes and associates primarily with the endoplasmic reticulum. The acidic amino terminus of Nogo-A is detected at the cytosolic face of cellular membranes and may contribute to inhibition of axon regeneration at sites of oligodendrocyte injury. A multivalent form of the N terminus of Nogo-A affects the morphology of both neurons and other cell types.
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分子量
- 180 kDa
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基因ID
- 57142
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途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
抗原
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