JRK 抗体 (N-Term)
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- 抗原 See all JRK 抗体
- JRK (Jerky Homolog (JRK))
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抗原表位
- N-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JRK antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Anti-JRK Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-JRK Antibody Picoband® (ABIN7603178). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human JRK, which shares 93.8% and 87.5% amino acid (aa) sequence identity with mouse and rat JRK, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product JRK Primary Antibody
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anti-Jerky Homolog (JRK) (AA 465-483) antibody
JRK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Jerky Homolog (JRK) (AA 1-568) antibodyJRK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
1. Donovan, G. P., Harden, C., Gal, J., Ho, L., Sibille, E., Trifiletti, R., Gudas, L. J., Toth, M. Sensitivity to jerky gene dosage underlies epileptic seizures in mice. J. Neurosci. 17: 4562-4569, 1997. 2. Moore, T., Hecquet, S., McLellann, A., Ville, D., Grid, D., Picard, F., Moulard, B., Asherson, P., Makoff, A. J., McCormick, D., Nashef, L., Froguel, P., Arzimanoglou, A., LeGuern, E., Bailleul, B. Polymorphism analysis of JRK/JH8, the human homologue of mouse jerky, and description of a rare mutation in a case of CAE evolving to JME. Epilepsy Res. 46: 157-167, 2001. 3. Morita, R., Miyazaki, E., Fong, C. G., Chen, X.-N., Korenberg, J. R., Delgado-Escueta, A. V., Yamakawa, K. JH8, a gene highly homologous to the mouse jerky gene, maps to the region for childhood absence epilepsy on 8q24. Biochem. Biophys. Res. Commun. 248: 307-314, 1998. Note: Erratum: Biochem. Biophys. Res. Commun. 250: 536 only, 1998. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- JRK (Jerky Homolog (JRK))
- 别名
- JRK (JRK 产品)
- 背景
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Synonyms: RING finger protein 186,RNF186,
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene. Alternative splicing results in multiple transcript variants.
- 分子量
- 65 kDa
- 基因ID
- 8629
- UniProt
- O75564
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