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GSTA3 抗体 (N-Term)

This anti-GSTA3 antibody is a 兔 多克隆 antibody detecting GSTA3 in WB 和 FACS. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7603173
发货至: 中国

Quick Overview for GSTA3 抗体 (N-Term) (ABIN7603173)

抗原

See all GSTA3 抗体
GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

适用

  • 41
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  • 2
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小鼠, 大鼠

宿主

  • 79
  • 10
  • 3

克隆类型

  • 83
  • 8
多克隆

标记

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This GSTA3 antibody is un-conjugated

应用范围

  • 86
  • 30
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  • 17
  • 13
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  • 8
  • 8
  • 5
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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 10
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    N-Term

    原理

    Anti-Gsta3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Gsta3 Antibody Picoband® (ABIN7603173). Tested in Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of mouse Gsta3, which shares 57.9% and 89.5% amino acid (aa) sequence identity with human and rat Gsta3, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    1. Board, P. G. Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4. Biochem. J. 330: 827-831, 1998. 2. Morel, F., Rauch, C., Coles, B., Le Ferrec, E., Guillouzo, A. The human glutathione transferase alpha locus: genomic organization of the gene cluster and functional characterization of the genetic polymorphism in the hGSTA1 promoter. Pharmacogenetics 12: 277-286, 2002. 3. Suzuki, T., Johnston, P. N., Board, P. G. Structure and organization of the human alpha class glutathione S-transferase genes and related pseudogenes. Genomics 18: 680-686, 1993.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

    别名

    Gsta3

    背景

    Synonyms: LIM/homeobox protein Lhx1, LIM homeobox protein 1, Homeobox protein Lim-1, hLim-1, LHX1, LIM-1, LIM1

    Tissue Specificity: Expressed in the brain, thymus, and tonsils. Expressed in samples from patients with chronic myeloid leukemia (CML) and in 58 % of acute myeloid leukemia (AML) cell lines.

    Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.

    分子量

    28 kDa

    基因ID

    2940

    UniProt

    P30115
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