GATA3 抗体 (N-Term)
Quick Overview for GATA3 抗体 (N-Term) (ABIN7603171)
抗原
See all GATA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-GATA3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GATA3 Antibody Picoband® (ABIN7603171). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human GATA3, which shares 86.4% and 90.9% amino acid (aa) sequence identity with mouse and rat GATA3, respectively.
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亚型
- IgG
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anti-GATA Binding Protein 3 (GATA3) antibody
GATA3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1A10A11 unconjugated
anti-GATA Binding Protein 3 (GATA3) (N-Term) antibodyGATA3 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 斑马鱼, 兔, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 1-260) antibodyGATA3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 103-200) antibodyGATA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 103-200) antibodyGATA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A4 unconjugated
anti-GATA Binding Protein 3 (GATA3) (pSer308) antibodyGATA3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (C-Term) antibodyGATA3 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 1-444) antibodyGATA3 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 1259CT707-136-102 unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 357-436) antibodyGATA3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GATA3-2442 unconjugated
anti-GATA Binding Protein 3 (GATA3) antibodyGATA3 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 4 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Joulin V, Bories D, Eleouet JF, Labastie MC, Chretien S, Mattei MG, Romeo PH (Jul 1991). "A T-cell specific TCR delta DNA binding protein is a member of the human GATA family" 2. Kouros-Mehr Hosein, Slorach EM, Sternlicht MD, Werb Z (December 2006). "GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland". Cell 127 (5): 1041-55. 3. Wilson BJ (2008). "Does GATA3 act in tissue-specific pathways? A meta-analysis-based approach". J. Carcinogenesis 7: 6. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GATA3 (GATA Binding Protein 3 (GATA3))
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别名
- GATA3
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背景
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Synonyms: Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, NSF
Background: Trans-acting T-cell-specific transcription factor GATA-3, also named HDR or GATA3, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.
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分子量
- 50 kDa
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基因ID
- 2625
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UniProt
- P23771
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途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
抗原
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