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FH 抗体 (N-Term)

This anti-FH antibody is a 小鼠单克隆 antibody detecting FH in WB 和 IHC. Suitable for 人, 小鼠, 大鼠和猴.

产品编号 ABIN7603168

发货至: 中国

Quick Overview for FH 抗体 (N-Term) (ABIN7603168)

抗原

See all FH 抗体

FH (Fumarate Hydratase (FH))

适用

人, 小鼠, 大鼠, 猴

宿主

小鼠

克隆类型

单克隆

标记

43
8
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This FH antibody is un-conjugated

应用范围

49
29
22
18
13
13
10
9
8
6
5
4
4
3
3
2
2
2
1
1

Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

9D8

Discover our top product FH Primary Antibody

抗原表位
15

8

6

5

4

3

3

2

2

1

1

1

1

1

1

1
N-Term

原理

Anti-FH Antibody Picoband® (monoclonal, 9D8)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-FH Antibody Picoband® (monoclonal, 9D8) (ABIN7603168). Tested in IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human FH, which shares 100% and 97.8% amino acid (aa) sequence identity with mouse and rat FH, respectively.

亚型

IgG2a
anti-Fumarate Hydratase (FH) (AA 45-188) antibody
FH 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fumarate Hydratase (FH) antibody
FH 适用: 人, 大鼠, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1F10 unconjugated

anti-Fumarate Hydratase (FH) antibody
KO Validated FH 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Fumarate Hydratase (FH) (Internal Region) antibody
Verified FH 适用: 人 WB, ELISA, IHC, EIA 宿主: 山羊 Polyclonal unconjugated

anti-Fumarate Hydratase (FH) (AA 33-510) antibody
FH 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5C12 unconjugated

anti-Fumarate Hydratase (FH) (AA 33-510) antibody
FH 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated

anti-Fumarate Hydratase (FH) (AA 33-510) antibody
FH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated

anti-Fumarate Hydratase (FH) (AA 42-185) antibody
FH 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fumarate Hydratase (FH) (AA 33-510) antibody
FH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D4 unconjugated

anti-Fumarate Hydratase (FH) (AA 33-510) antibody
FH 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C5 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
1. Begley TP, McMurry J (2005). The organic chemistry of biological pathways. Roberts and Co. Publishers. 2. Weaver T (October 2005). "Structure of free fumarase C from Escherichia coli". ActaCrystallogr. D. 61 (Pt 10): 1395-401.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

FH (Fumarate Hydratase (FH))

别名

FH

背景

Synonyms: Fumarate hydratase, mitochondrial, Fumarase, FH,
Tissue Specificity: Expressed in red blood cells, underexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology.
Background: Fumarase (or fumaratehydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety. This enzyme participates in 2 metabolic pathways: citric acid cycle, reductive citric acid cycle (CO2 fixation), and is also important in renal cell carcinoma. Mutations in this gene have been associated with the development of leiomyomas in the skin and uterus in combination with renal cell carcinoma.

分子量

48 kDa

基因ID

2271

UniProt

P07954

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